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陈博

副主任医师

专家门诊: 电 话:010-53968000

个人简介

  姓名:陈博

  职称:副主任医师、副教授    

        

  技术擅长:

  1. 全方位形体雕塑治疗:全身脂肪抽吸;吸脂术后修复;自体脂肪隆胸、隆臀;全腹壁整形术;外伤后体表畸形/凹陷的综合治疗;肉毒素瘦肩、瘦小腿。

  2. 眼部整形美容手术:双眼皮、眼袋、提眉等美容手术;眼周畸形、软组织缺损修复。  

  3. 面颈部年轻化综合治疗:自体脂肪、玻尿酸注射填充;肉毒素注射除皱、瘦脸;面颈部除皱手术。

  4.瘢痕、瘢痕疙瘩及各类体创伤、表肿物的手术专科治疗:瘢痕美学治疗;瘢痕疙瘩的综合治疗;各类创伤瘢痕的修复重建治疗;体表肿物的手术治疗。  


  简介:

  整形外科学博士,2012年毕业于上海交通大学医学院附属第九人民医院整复外科,师从我国整形外科领军人物刘伟教授、曹谊林教授。主持包括国家自然科学基金、北京市自然科学基金在内的科研项目5项。在国内外发表中英文文章50余篇,其中第一作者或通讯作者发表SCI文章20篇。参编专著2部《整形美容外科手术失误及处理》(第二版),《整形美容外科学全书》,作为副主译翻译英文专著1部《Rejuvenation of the aging face》。完成各类整形美容、修复重建手术及注射治疗上万例。


  出诊时间:周五上午


  联系方式:微博:八大处整形陈博


  发表论文

  1.Chen B, Ding JP, Jin J, et al. Continuous Tension Reduction to Prevent Keloid Recurrence After Surgical Excision: Preliminary Experience in Asian Patients. Dermatol Ther. 2020;33:e13553.

  2.Chen B, Ding J, Zhao Z, et al. Mechanical Loading Improves Engineered Tendon Formation with Muscle-Derived Cells: An In Vivo Analysis. Plast Reconstr Surg. 2018;142:685e-693e.

  3.Chen B, Ding J, Zhang W, et al. Tissue Engineering of Tendons: A Comparison of Muscle-Derived Cells, Tenocytes, and Dermal Fibroblasts as Cell Sources. Plast Reconstr Surg. 2016;137:536e-544e.

  4.Chen B, Wang B, Zhang WJ, et al. Macromolecular crowding effect on cartilaginous matrix production: a comparison of two-dimensional and three-dimensional models. Tissue Eng Part C Methods. 2013;19(8):586-  95.

  5.Chen B, Wang B, Zhang WJ, et al. In vivo tendon engineering with skeletal muscle derived cells in a mouse model. Biomaterials. 2012;33:6086-97.

  6.Wang D, Ding J, Chen B, et al. Synergistic effects of myogenic cells and fibroblasts on the promotion of engineered tendon regeneration with muscle derived cells. Connect Tissue Res. 2021;24:1-10.

  7.Wang D, Ding J, Jiang Y, Liu Y, Chen B. Continuous tension reduction technique in facial acar management: A comparison of W-plasty and straight-line closure on aesthetic effects in Asian patients. Int Wound J. 2021 Oct 15. 

  8.Wang LZ, Ding JP, Yang MY, Chen B. Forty-five cases of chest keloids treated with subcutaneous super-tension-reduction suture combined with postoperative electron-beam irradiation. Dermatol Surg. 2014; 40:1378-1384.

  9.Wang LZ, Ding JP, Yang MY, Chen DW, Chen B. Treatment of facial post-burn hyperpigmentation using Micro-plasma radio frequency technology. Lasers Med Sci. 2015;30:241-245.

  10.Wang D, Chen B. Human CD206+ Macrophages Show Antifibrotic Effects on Human Fibroblasts through an IL-6-Dependent Mechanism In Vitro. Plast Reconstr Surg. 2021;148:497e-498e.

  11.Wang D, Chen B. Quality and Quantity-Cultured Human Mononuclear Cells Improve Human Fat Graft Vascularization and Survival in an In Vivo Murine Experimental Model. Plast Reconstr Surg. 2021 Oct 18. 

  12.Wang D, Chen B. The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars. Aesthetic Plast Surg. 2021 Mar 25. 

  13.Wang D, Chen B. Botulinum Toxin Type A Injection for Mammoplasty and Abdominoplasty Scar Management: A Split-Scar Double-Blinded Randomized Controlled Study. Aesthetic Plast Surg. 2021 Mar 17. 

  14.Wang D, Chen B. The Effects of Subcutaneously Injected Novel Biphasic Cross-Linked Hyaluronic Acid Filler: An In Vivo Study. Aesthetic Plast Surg. 2021 Mar 10. 

  15.Wang D, Chen B. Non-significant Effects of the Geometric Shape of Autologous Cartilage Grafts on Tissue Healing: An Animal Study. Aesthetic Plast Surg. 2021;45:1965-1966. 

  16.Wang D, Chen B. Comment on: “Efficacy and Safety of Lyophilized Articular Cartilage Matrix as an Injectable Facial Filler”. Aesthetic Plast Surg. 2021;45:1957-1958. 

  17.Wang D, Chen B. Comment on: “Striae Distensae: In Vitro Study and Assessment of Combined Treatment with Sodium Ascorbate and Platelet-Rich Plasma on Fibroblasts”. Aesthetic Plast Surg. 2021;45:1961-1962. 

  18.Wang D, Chen B. Comment on: Smoking and Physical Activity Significantly Influence Stromal Vascular Fraction Cell Yield and Viability. Aesthetic Plast Surg. 2021 Apr 9. 

  19.Wang D, Chen B. Comment on: “The Treatment of Capsular Contracture Around Breast Implants Induced by Fractionated Irradiation: The Collagenase of the Bacterium Clostridium Histolyticum as a Novel Therapeutic Approach”. Aesthetic Plast Surg. 2021 Apr 2. 

  20.Wang D, Chen B. Human Spheroids from Adipose-Derived Stem Cells Induce Calvarial Bone Production in a Xenogeneic Rabbit Model. Ann Plast Surg. 2022 Feb 1;88(2):250. 


  学习工作履历:

  2007-2012,上海交通大学医学院附属第九人民医院,硕博连读 

  2012-2020,中国医学科学院整形外科医院,住院医师,主治医师

  2020至今,中国医学科学院整形外科医院,副主任医师   

     

  学术成果:

  吸脂及自体脂肪移植领域:1)提出快速康复技术在大面积脂肪抽吸中的应用,极大程度提高了吸脂术后的患者舒适度,让术后患者尽快恢复正常工作生活。2)率先开展成分脂肪移植,用于陈旧性瘢痕的治疗。

  再生医学领域:国际上率先提出应用肌源性细胞转分化为肌腱系细胞,构建工程化肌腱修复肌腱缺损,并开展了大量的基础及动物实验研究;构建自体肌腱组织修复外伤后肌腱缺损已开展临床试验。

  瘢痕治疗领域:1)基于系统的力学刺激对组织再生的实验研究,国际上率先提出持续瘢痕减张技术在瘢痕美容以及病理性瘢痕治疗中的应用。2)建立了动态力学刺激促进病理性瘢痕形成的动物模型。3)国际上率先开展持续减张技术抑制瘢痕疙瘩复发的研究,为不适合术后放疗的瘢痕疙瘩患者治疗提供了一种新的选择。


  主持科研项目:

  1. 国家自然科学基金 (31303851)《肌肉来源细胞再生肌腱组织的相关分子机制及大动物体内研究》,2014-2016,项目负责人。

  2. 北京市自然基金 (7144239)《FGF-4/FGF-8调控肌肉来源细胞向肌腱系转分化的相关机制研究》,2014-2015,项目负责人。

  3. 北京协和医学院“协和青年科学基金”《成纤维细胞生长因子通路调控肌源性干细胞成熟分化的相关机制》,2013-2014,项目负责人。

  4. 北京协和医学院“协和青年科学基金滚动支持项目”《成纤维细胞生长因子通路调控肌源性干细胞成熟分化的相关机制》,2014-2015,项目负责人。

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